Corruption is a borderless crime. Perpetrators of corruption often work across several jurisdictions. This makes it necessary for partnership among global anti-corruption agencies.

The OSP is a designated technical institution for the implementation of the United Nations Convention against Corruption (UNCAC) in Ghana. The Office is also active on other reputable anti-corruption platforms. International cooperation deepens mutual legal assistance and provides a platform for learning and sharing, and technical assistance among anti-corruption agencies across countries.